Drugs can become deadly when combined. Clearly the most dangerous drugs to mix with alcohol are other sedatives, including antihistamines found in some cold medicines. Anti-anxiety medications may cause severe drowsiness with alcohol. In combination with antibiotics they can cause nausea, vomiting, headache, or even convulsions. Also, alcohol increases the sedative effects of some antidepressants, which impairs both physical and mental skills. As for women, oral contraceptives slow down the rate at which alcohol is eliminated from the body. A woman on the pill can therefore expect to feel the sedating effects of alcohol for a longer period than a woman who is not on the pill. As with all medication it is advised that you consult with your provider.